Numb and NumbL inhibit melanoma tumor growth by influencing the immune microenvironment
Abstract Objective Many investigation have sought to identify therapeutic targets and treatment strategies for skin cutaneous melanoma (SKCM).Numb, an endocytic adaptor protein, is known to act as a tumor suppressor in various human cancers.However, the roles of Numb and its homolog NumbL in immune microenvironment, and their effect on melanoma rem